Domain Response is a tool that is designed to help you automate the investigation for a domain. This tool is specificly designed to automated phishing domain investigations. However it can be used for every domain to gather all domain information needed. This can help to classify if a domain is malicious.
Why do you think that https://github.com/KnightmareVIIVIIXC/AIO-Firebog-Blocklists is a good alternative to Domain-Response