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musescore-microtonal-edo-plugin
Microtonal MuseScore plugin to retune notes in any EDO. Deprecated, see musescore-xen-tuner (link below).
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Sibelius and MuseScore can both natively notate quarter tones, at least, and I think MuseScore might actually have more options for alternative microtonal accidentals - Sibelius doesn't seem to support custom accidentals, either. Sibeilus comes with a plugin that adds MIDI codes for microtonal playack, but I don't think MuseScore natively supports microtonal playback. There is a microtonal plugin for MuseScore that's endorsed on the Xenharmonic Wiki, which is a great resource for this kind of stuff.