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Thruk
Thruk is a multibackend monitoring webinterface for Naemon, Nagios, Icinga and Shinken using the Livestatus API.
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openITCOCKPIT
openITCOCKPIT is an Open Source system monitoring tool built for different monitoring engines like Nagios, Naemon and Prometheus.
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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
But there are also other solutions out there that can manage the configs for you such as Thruk or Adagios.
In my professional life I'm part of the open source project openITCOCKPIT. It will handle all the Nagios configuration (and much more) for you.
NOTE:
The number of mentions on this list indicates mentions on common posts plus user suggested alternatives.
Hence, a higher number means a more popular project.