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You don't have to let the spikes from the switcher get very far.
Here's the schematic for a switcher I designed.[1] This is a strange application - USB power in, 120V out, to drive an antique Teletype machine. Without any filtering, there would be huge spikes in the DC across C1-C2. But it didn't take much filtering to fix that. There's a small ferrite bead at L2, and an RC filter at the snubber at R1-C7. The back to back Zeners are to absorb inductive kickback from the output electromagnet. That's the output side. On the input side, there's more noise suppression, to prevent injecting noise back into the USB power source, which is usually a laptop here. Note L1 and C12. Those are all tiny surface mount parts, total cost in quantity maybe US$0.20.
It's an exercise in LTSpice to get the values right and make the DC power smooth DC, in both voltage and current. This is well understood.
There are radio hams using this thing, and they report it's not blithering in the RF spectrum.
[1] https://github.com/John-Nagle/ttyloopdriver/blob/master/boar...