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OrdinaryDiffEq.jl
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There has been a lot of research in Runge Kutta methods in the last couple decades which resulted in all kind of specialized Runge Kutta methods. You have high order ones, RK methods for stiff problems, embedded RK methods which benefit from adaprive step size control, RK-Nystrom methods for second order Problems, symplectic RK methods which preserve energy (eg. hamiltonian) ando so on. If you are interested in the numerics and the use cases I highly recommend checking out the Julia Libary OrdinaryDiffEq (https://github.com/SciML/OrdinaryDiffEq.jl). If you look into the documentation you find A LOT of implemented RK methods for all kind of use cases.