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The main problem in my mind with the Lightning network is that in order increase transaction speed, it is reducing the decentralization by requiring participants to trust the other network operators that they create channels with. For the lightning network to really scale to a global payment system, we would need large central hubs for the payments to route through and you would end up with a poor imitation of the centralized banking system that bitcoin is attempting to avoid.
This page is a good collection of issues and criticisms of LN: https://github.com/davidshares/Lightning-Network