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I think the main thing to understand is that Debian is reproducible as a consequence of significant unenforced contracts around what the pristine build environment will be, what the state of the package repo will be when dependencies are fetched and installed, and so on (see: https://www.debian.org/doc/debian-policy/ch-source.html#repr...). Your local dpkg-buildpackage invocation has pretty much a 0% chance of being a bit-for-bit reproduction of what you pulled from the archive unless you cooperate with all this ceremony.
Nix, on the other hand, is reproducible by default. If you `nix build ` you are automatically getting a local build that takes place in the same hermetic sandbox as the build you pulled from cache.nixos.org, and will be identical or very close to it. (Contrary to popular belief, not all of nixpkgs is reproducible— many packages require patching for various sources of nondeterminism, and this is an ongoing effort: https://github.com/NixOS/nixpkgs/labels/6.topic%3A%20reprodu...)