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Since you are ready to learn the information flow of WPF (which not a small task). I would suggest you use a Flutter as a frontend library as it is cross-platform and has far greater support than pyqt\tikinter\dearpygui. Use socket.io (has ports in many languages) to communicate between flutter and python.
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DearPyGui
Dear PyGui: A fast and powerful Graphical User Interface Toolkit for Python with minimal dependencies
try using DearPyGui , it is similar to tkinter but has a bigger feature set
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Appwrite
Appwrite - The Open Source Firebase alternative introduces iOS support . Appwrite is an open source backend server that helps you build native iOS applications much faster with realtime APIs for authentication, databases, files storage, cloud functions and much more!
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