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I would say, head over to MDN, and look up WebAudio and WebMIDI. You can do the whole thing with no additional downloads, if you already have Chrome installed.
Sonic Pi https://sonic-pi.net/ may be worth checking out. It offers fundamental coding constructs through music and sound design. At the very least it’s a free creative tool to play around with for musical ideas and performance
NOTE:
The number of mentions on this list indicates mentions on common posts plus user suggested alternatives.
Hence, a higher number means a more popular project.