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Are you looking for something hosted by another organization? I'd say just use the old version of Reddit from when it was still open source as long as you're willing to self-host (https://github.com/reddit-archive/reddit/wiki/Install-guide). I believe that is what Less Wrong originally did. The features that Reddit has added since don't seem useful to me anyway.
https://github.com/LemmyNet/lemmy
"... Lemmy is similar to sites like Reddit, Lobste.rs, or Hacker News: you subscribe to forums you're interested in, post links and discussions, then vote, and comment on them. Behind the scenes, it is very different; anyone can easily run a server, and all these servers are federated (think email), and connected to the same universe, called the Fediverse."
The software is QPixel. It was built specifically to be an open-source discussion system a la Stack Exchange.
The largest public instance of it that I know of is codidact.com; codidact.org is the sponsoring organization.
https://github.com/codidact/qpixel
The Lobsters codebase is available, it's a straightforward Rails app with few dependencies: https://github.com/lobsters/lobsters
In the bioinformatics sphere there is this MIT-licensed Stack Exchange clone: https://github.com/ialbert/biostar-central