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Here https://github.com/dietmarwo/fast-cma-es/blob/master/tutorials/Quant.adoc is a new tutorial how to apply optimization in the context of simulated quantum algorithms. It is based on https://qiskit.org/textbook/ch-applications/vqe-molecules.html#Example-with-a-Single-Qubit-Variational-Form but provides more reliable methods utilizing parallelism. This makes not much sense (yet) when the backend is a real quantum computer, but most simulators scale bad when using multi-threading or an GPU. So it is better to switch parallelism off for the simulation and utilize the better scaling parallel optmization provides, specially if a modern many-core CPU is available.