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"The Nix way" would be to use Home Manager, but it's possible to only use nix-env or nix profile to install packages.
Another comment mentioned nixGL. That's needed for GPU acceleration, or apps like Kitty won't work.
You might want to look at Distrobox (Docker/Podman), it's basically a set of helper scripts that make containers more transparent to the use. It also has an option to export an application from the container and make it available to use from the base OS.