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You also have the option to go with a port of VCL: https://github.com/Embarcadero/DelphiVCL4Python
Here is an example of one theme that looks just like out of the box pyqt: https://github.com/rdbende/Azure-ttk-theme
What are you trying to build? Is it web application or desktop application or you would like to add GUI to Jupyter Notebook? For adding GUI to notebooks I can recommend Mercury - it is very simple. You just add YAML with definition of widgets.
NOTE:
The number of mentions on this list indicates mentions on common posts plus user suggested alternatives.
Hence, a higher number means a more popular project.