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DearPyGui
Dear PyGui: A fast and powerful Graphical User Interface Toolkit for Python with minimal dependencies
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If you want more low-level GUI,Dear PyGui is nice.
For a quick PoC that is really nice looking and friendly, Streamlit is a good choice.
Check out Bokeh https://bokeh.org/
Does anyone use Dear ImGui with Python (pyimgui?) ? I tried it with C++ and it looks like a neat solution.