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See, for example, Sylvain Kerkour's 42 Companies using Rust in production from last April or omarabid/rust-companies or the Production users page on the Rust website itself that others have been linking.
I know Microsoft is putting effort into providing documentation and API bindings for using Rust on Windows and have used it for a component or two, though what beside one of their Azure components is unclear.
Amazon is putting effort into it in various ways, including an AWS SDK and being one of the founding members of the Rust Foundation along with Google, Microsoft, Mozilla, and Huawei. The company formerly known as Facebook also joined as a platinum supporter later. (Members list)