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Some folks have mentioned fastapi, which is a good call. If you want to be more extreme about performance, under the covers, fastapi is a combination of starlette and pydantic plus various other goodies. You can build a pure starlette-based API if complete speed is of the essence and you want to stick with python.
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InfluxDB
InfluxDB high-performance time series database. Collect, organize, and act on massive volumes of high-resolution data to power real-time intelligent systems.
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NOTE:
The number of mentions on this list indicates mentions on common posts plus user suggested alternatives.
Hence, a higher number means a more popular project.
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