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Anyway, based on my experience, I say just pick a distro and run with it. You can always switch distros later if you want. Just make sure to keep track of your setup/configs in some sort of repository or storage system (here's mine).
Xanmod: Does quite well in Phoronix benchmarks
The topic makes for some pretty spicy reading 🌶️🌶️🌶️🌶️🌶️ but to cut a long story short, at the time of writing (22/08/2021), Nvidia's proprietary drivers don't fully support an API called Generic Buffer Management (GBM) - A more or less universally agreed upon API required most Wayland compositor libraries (like the official version of wlroots, used by swaywm) and supported by more or less every other hardware manufacturer's drivers. This means quite a lot of modern desktop environments aren't supported properly when you're using an Nvidia GPU.
I patched my kernel with Linux Zen. In addition to the acs_override patch, it claims to modify Linux a way that better caters it to highly interactive realtime experiences (E.g. Gaming or personal desktop use). There are claims online that it reduces perceived "stutter" and reduces the minimum FPS of games under certain workloads.