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Longer answer: it depends. There are specialty frameworks in python that are really good for messing around with games. For instance the existence of pyxel is delightful. But is it going to be a track to releasing an indie game that can get you paid? Probably not. But if you can think of a game that you want to execute in python or using particular python libraries then absolutely do so if you're productive in python.
NOTE:
The number of mentions on this list indicates mentions on common posts plus user suggested alternatives.
Hence, a higher number means a more popular project.