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Looks like you have a misunderstanding about the right-most column. Don't think of the cell values as vectors of length=N elements, c("gene1", "gene2", ..."geneN"). Instead, think of each cell as a character string (vector of length=1), "gene 1, gene 2, ... geneN". Finding specific sequence of characters within a string is different from finding matching elements of vectors. Without changing the column, you can use regular expressions and base R string functions and/or stringr if you're more comfortable with tidyverse.
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