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emm maybe try this ? https://github.com/honghaier-game/TKinterDesigner
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Good use of PyInstaller or PyOxidizer can give you a head start. Don't forget, Dropbox, Netflix, Reddit, Spotify use a ton of python, and the Dropbox client is mostly python.
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InfluxDB
Power Real-Time Data Analytics at Scale. Get real-time insights from all types of time series data with InfluxDB. Ingest, query, and analyze billions of data points in real-time with unbounded cardinality.
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Meh, Dash is OK. These days, my go-to is voila, which basically supports anything you can serve via a jupyter notebook (including plotly). Gives you access to the entire ipywidgets, bokeh, and holoviz ecosystems. Just make a notebook with some UI elements in it and bam: you've got a webapp.
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If you do any 3d printing: I think most of the FreeCAD and Cura UIs are actually python. And although open source, Cura is absolutely a commercial product (via Ultimaker).
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Or have a Look into „eel“. https://github.com/ChrisKnott/Eel
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fpm
Effing package management! Build packages for multiple platforms (deb, rpm, etc) with great ease and sanity.
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WorkOS
The modern identity platform for B2B SaaS. The APIs are flexible and easy-to-use, supporting authentication, user identity, and complex enterprise features like SSO and SCIM provisioning.