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Take a look at Dash https://plotly.com/dash/. It works perfectly with flask, cause it's use flask. Works for me pretty fine, large datasets are no problem.
Streamlit — The fastest way to build data apps in Python
Use something like Streamlit. https://streamlit.io/
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NOTE: The number of mentions on this list indicates mentions on common posts plus user suggested alternatives. Hence, a higher number means a more popular project.
How can I build interactive plots using Matplotlib/Numpy?
2 projects | reddit.com/r/learnpython | 4 Nov 2022
What tools are available for personal use?
2 projects | reddit.com/r/datascience | 7 Jun 2021
4 Streamlit Alternatives for Building Python Data Apps
3 projects | dev.to | 8 Feb 2023
Sharing interactive Plotly graphs
1 project | reddit.com/r/datascience | 18 Nov 2022
Containerizing Shiny for Python and Shinylive Applications
4 projects | dev.to | 10 Nov 2022