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Mail-in-a-Box
Mail-in-a-Box helps individuals take back control of their email by defining a one-click, easy-to-deploy SMTP+everything else server: a mail server in a box.
The closest direct competitor to mailcow would be mailinabox. But I am not sure what the memory profile of that is going to be.
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Judoscale
Save 47% on cloud hosting with autoscaling that just works. Judoscale integrates with Django, FastAPI, Celery, and RQ to make autoscaling easy and reliable. Save big, and say goodbye to request timeouts and backed-up task queues.
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docker-mailserver
Production-ready fullstack but simple mail server (SMTP, IMAP, LDAP, Antispam, Antivirus, etc.) running inside a container.
I can recommend Docker mailserver (it also works with Podman). It is already pretty lightweight but you can even make it lighter and it has an active community as well as regular updates.