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InfluxDB
Purpose built for real-time analytics at any scale. InfluxDB Platform is powered by columnar analytics, optimized for cost-efficient storage, and built with open data standards.
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https://d3js.org/ (a bit lower-level but more flexible)
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There are options for writing Python and transpiling it into JavaScript but, frankly, they suck (https://www.transcrypt.org/).
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There's a Python runtime that runs on WebAssembly (https://github.com/pyodide/pyodide). I have no idea what it's like, I've never used it.
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There's Shiny for Python - originally for R - but it's only Alpha status: https://shiny.rstudio.com/py/
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SaaSHub
SaaSHub - Software Alternatives and Reviews. SaaSHub helps you find the best software and product alternatives
NOTE:
The number of mentions on this list indicates mentions on common posts plus user suggested alternatives.
Hence, a higher number means a more popular project.