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Qt story was always quite bad in Ruby land. I don't think there is any binding working with Qt5. There is ruby-qml, but it wasn't updated in 3 years.
Have used tk for a windows GUI https://github.com/ruby/tk A bit old school style, but works.
Gtk3 has always been very dependable for me. Fairly easy to approach and lots of samples. https://github.com/ruby-gnome/ruby-gnome
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