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Not specially something that you cannot do without WASM but at $WORK we are using a WASM build of Skia [0] to render canvas from nodejs.
Why use WASM ? Because we wanted to stay close to our stack (ie. calling wasm from nodejs). Do it work ? Yes, memory consumption is quite heavy though (each WASM module have its own heap that can quickly grow).
However we are looking to directly use Skia now and avoid the overhead of WASM so i think its a nice solution in the beginning but you might want to ditch it later on.
[0]: https://github.com/google/skia/tree/main/modules/canvaskit
CUE has someone working on WASM to support writing code in any language, so it can be used and shipped without compilation in the scripting layer