Top 23 Python multi-agent Projects

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1. deer-flow

   1 20 77,199 9.9 Python

   An open-source long-horizon SuperAgent harness that researches, codes, and creates. With the help of sandboxes, memories, tools, skill, subagents and message gateway, it handles different levels of tasks that could take minutes to hours.

   

   Project mention: Running Gemma 4 26B at 5 tokens/SEC on a 13-year-old Xeon with no GPU | news.ycombinator.com | 2026-07-15

2. SaaSHub

   www.saashub.com featured

   SaaSHub - Software Alternatives and Reviews. SaaSHub helps you find the best software and product alternatives

   

3. MetaGPT

   2 39 69,384 9.1 Python

   🌟 The Multi-Agent Framework: First AI Software Company, Towards Natural Language Programming

   

4. CowAgent

   3 1 46,024 9.8 Python

   Open-source super AI assistant & Agent Harness. Plans tasks, runs tools and skills, self-evolves with memory and knowledge. Multi-model, multi-channel. Lightweight, extensible, one-line install. (formerly chatgpt-on-wechat)

   

5. agentscope

   4 4 27,981 9.6 Python

   Build and run agents you can see, understand and trust.

   

   Project mention: All Data and AI Weekly #207: 15 Sept 2025 | dev.to | 2025-09-15

   GitHub Link: https://github.com/agentscope-ai/agentscope Summary: Agentscope is an agent-oriented programming library that makes it easier to build LLM applications. It's designed to be "developer-centric" with features like asynchronous execution, parallel tool calls, and real-time steering. It offers a transparent approach where prompt engineering and API invocation are fully visible and controllable. Why it's important: Agentscope, along with its related libraries like agentscope-runtime and agentscope-studio, provides a comprehensive toolkit for not only developing but also deploying and visualizing agent-based applications.

6. adk-python

   5 62 20,645 9.9 Python

   An open-source, code-first Python toolkit for building, evaluating, and deploying sophisticated AI agents with flexibility and control.

   

   Project mention: Building a Document-RAG Agent on GCP's Agent Development Kit (ADK) | dev.to | 2026-07-14

   Google's Agent Development Kit (ADK)

7. Vibe-Trading

   6 3 18,900 9.7 Python

   "Vibe-Trading: Your Personal Trading Agent"

   

   Project mention: Codex Deleted Real Files. The Fix? A Flag You Didn't Set. | dev.to | 2026-07-16

   Now extend this pattern to something that should terrify you. HKUDS/Vibe-Trading is a GitHub repository with 24,000 stars, trending at +721 stars per day as of this writing. It is an autonomous trading agent powered by LLMs that executes trades on broker APIs -- including perpetual futures on platforms like Hyperliquid where leverage amplifies losses.

8. agent-framework

   7 18 12,187 9.9 Python

   A framework for building, orchestrating and deploying AI agents and multi-agent workflows with support for Python and .NET.

   

   Project mention: What We Learned Scanning Microsoft's Public Agent Framework Repository | dev.to | 2026-06-13

   Clear Code Intelligence scanned a public Microsoft repository: microsoft/agent-framework.

9. PraisonAI

   8 3 8,451 10.0 Python

   PraisonAI 🦞 — Hire a 24/7 AI Workforce. Stop writing boilerplate and start shipping autonomous self-improving agents that research, plan, code, and execute tasks. Deployed in 5 lines of code with built-in memory, RAG, and support for 100+ LLMs.

   

10. solace-agent-mesh

    9 2 4,964 9.9 Python

    An event-driven framework designed to build and orchestrate multi-agent AI systems. It enables seamless integration of AI agents with real-world data sources and systems, facilitating complex, multi-step workflows.

    

    Project mention: Ditch the Monolith: Build Scalable AI Teams with Solace Agent Mesh | dev.to | 2025-10-10

    View the Project on GitHub

11. ag2

    10 9 4,783 9.8 Python

    AG2 (formerly AutoGen): The Open-Source AgentOS.Join us at: https://discord.gg/sNGSwQME3x

    

    Project mention: Give Your AG2 Agents a UI with AG‑UI and CopilotKit | dev.to | 2026-02-26

    AG2 (formerly AutoGen) changes that. It provides a shared runtime where specialized agents with defined roles, tools and conversation patterns can collaborate as one coordinated team across models and even frameworks.

12. rlcard

    11 5 3,508 2.6 Python

    Reinforcement Learning / AI Bots in Card (Poker) Games - Blackjack, Leduc, Texas, DouDizhu, Mahjong, UNO.

    

13. agentUniverse

    12 1 2,308 8.4 Python

    agentUniverse is a LLM multi-agent framework that allows developers to easily build multi-agent applications.

    

14. gym-pybullet-drones

    13 4 2,082 7.2 Python

    PyBullet Gymnasium environments for single and multi-agent reinforcement learning of quadcopter control

    

15. on-policy

    14 12 2,060 4.2 Python

    This is the official implementation of Multi-Agent PPO (MAPPO).

    

16. MAgent

    15 2 1,761 0.0 Python

    A Platform for Many-Agent Reinforcement Learning

    

17. concordia

    16 1 1,564 9.4 Python

    A library for generative social simulation (by google-deepmind)

    

18. ChatArena

    17 6 1,549 2.3 Python

    ChatArena (or Chat Arena) is a Multi-Agent Language Game Environments for LLMs. The goal is to develop communication and collaboration capabilities of AIs.

    

19. skrl

    18 7 1,081 8.0 Python

    Modular Reinforcement Learning (RL) library (implemented in PyTorch, JAX, and NVIDIA Warp) with support for Gymnasium/Gym, NVIDIA Isaac Lab, MuJoCo Playground and other environments

    

20. AgileRL

    19 12 935 8.8 Python

    Streamlining reinforcement learning with RLOps. State-of-the-art RL algorithms and tools, with 10x faster training through evolutionary hyperparameter optimization.

    

21. maro

    20 9 913 0.0 Python

    Multi-Agent Resource Optimization (MARO) platform is an instance of Reinforcement Learning as a Service (RaaS) for real-world resource optimization problems.

    

22. neuro-san-studio

    21 2 828 9.9 Python

    A playground for neuro-san

    

23. ainativelang

    22 2 822 9.8 Python

    AINL helps turn AI from "a smart conversation" into "a structured worker." It is designed for teams building AI workflows that need multiple steps, state and memory, tool use, repeatable execution, validation and control, and lower dependence on long prompt loops. AINL is a compact, graph-canonical, AI-native programming system for (READ: README)

    

    Project mention: Project Glasswing: An Initial Update | news.ycombinator.com | 2026-05-22

    And to consider AI agents are still mostly entirely limited to generating code in programming languages designed to be written, tested and debugged by humans.

    Here are two experimental exceptions:

    https://github.com/vercel-labs/zerolang

    https://github.com/sbhooley/ainativelang

24. powermem

    23 6 757 9.5 Python

    PowerMem: AI Memory Plugin— Accurate, Agile, Affordable. Make AI Agent smarter.

    

    Project mention: Stop Editing JSON by Hand | dev.to | 2026-05-24

    TL;DR: ClawMaster is an open-source OpenClaw companion with a setup wizard, channel and model management, cost observability, Skill hosting, and PowerMem-backed memory. Install with two commands, then open http://localhost:16223.

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• A note from our sponsor - SaaSHub
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