Python high-performance-computing

Open-source Python projects categorized as high-performance-computing
Edit details
Python parallel-computing Machine Learning Jax GPU
SaaSHub - Software Alternatives and Reviews
SaaSHub helps you find the best software and product alternatives
www.saashub.com
featured

Top 14 Python high-performance-computing Projects

Python logo
high-performance-computing

  1. metaflow

    Build, Manage and Deploy AI/ML Systems

    Project mention: Metaflow: Build, Manage and Deploy AI/ML Systems | news.ycombinator.com | 2025-07-16

    Stay tuned! We have some cool new features coming soon to support agentic workloads (teaser: https://github.com/Netflix/metaflow/pull/2473)

    If you are curious, join the Metaflow Slack at http://slack.outerbounds.co and start a thread on #ask-metaflow

  2. SaaSHub

    SaaSHub - Software Alternatives and Reviews. SaaSHub helps you find the best software and product alternatives

    SaaSHub logo

  3. tf-quant-finance

    High-performance TensorFlow library for quantitative finance.

  4. openmc

    OpenMC Monte Carlo Code

  5. prometeo

    An experimental Python-to-C transpiler and domain specific language for embedded high-performance computing

  6. dace

    DaCe - Data Centric Parallel Programming

  7. pysph

    A framework for Smoothed Particle Hydrodynamics in Python

  8. mpi4jax

    Zero-copy MPI communication of JAX arrays, for turbo-charged HPC applications in Python :zap:

  9. pyhpc-benchmarks

    A suite of benchmarks for CPU and GPU performance of the most popular high-performance libraries for Python :rocket:

  10. Fast-Poisson-Image-Editing

    A fast poisson image editing implementation that can utilize multi-core CPU or GPU to handle a high-resolution image input.

  11. hongbomiao.com

    A personal research and development (R&D) lab that facilitates the sharing of knowledge.

  12. torchquad

    Numerical integration in arbitrary dimensions on the GPU using PyTorch / TF / JAX

  13. PSyclone

    PSyclone is a source-to-source Fortran compiler designed to programmatically optimise, parallelise and instrument HPC applications via user-provided transformation scripts.

  14. AeroJAX

    AeroJAX: A differentiable, structure-preserving framework for real-time flow simulation, control, and inverse design. Architected for neural operator integration and latent-space acceleration. Built with JAX.

    Project mention: Building a Real-Time CFD Framework in JAX (AeroJAX) | dev.to | 2026-05-14

    👉 GitHub Repository: https://github.com/arriemeijer-creator/AeroJAX

  15. python-performance-playground

    Performance analysis of Python snippets for scientific computing

NOTE: The open source projects on this list are ordered by number of github stars. The number of mentions indicates repo mentiontions in the last 12 Months or since we started tracking (Dec 2020).

Python high-performance-computing discussion

Log in or Post with

Python high-performance-computing related posts

  • Building a Real-Time CFD Framework in JAX (AeroJAX)

    1 project | dev.to | 14 May 2026

  • Show HN: Interactive fluid simulation in Jax using Brinkman penalization

    1 project | news.ycombinator.com | 13 May 2026

  • FlashAttention-3: Fast and Accurate Attention with Asynchrony and Low-Precision

    5 projects | news.ycombinator.com | 11 Jul 2024

  • Can LLMs learn from a single example?

    2 projects | news.ycombinator.com | 5 Sep 2023

  • Are there any libraries that can easily convert Python to C/C#/or C++? Ones where a person doesn't have to "calibrate" it, just, pip install library and then they can have their Python code in C,C#,or C++?

    1 project | /r/learnpython | 6 Apr 2023

  • FPGA high-level programming

    1 project | /r/FPGA | 2 Feb 2023

  • how much does it actually cost in terms of computer power for open AI to respond

    1 project | /r/OpenAI | 22 Dec 2022
  • A note from our sponsor - SaaSHub
    www.saashub.com | 9 Jun 2026
    SaaSHub helps you find the best software and product alternatives Learn more →

Index

What are some of the best open-source high-performance-computing projects in Python? This list will help you:

# Project Stars
1 metaflow 10,116
2 tf-quant-finance 5,383
3 openmc 1,030
4 prometeo 654
5 dace 584
6 pysph 537
7 mpi4jax 529
8 pyhpc-benchmarks 336
9 Fast-Poisson-Image-Editing 303
10 hongbomiao.com 297
11 torchquad 226
12 PSyclone 133
13 AeroJAX 47
14 python-performance-playground 4

Sponsored
SaaSHub - Software Alternatives and Reviews
SaaSHub helps you find the best software and product alternatives
www.saashub.com
Loading...