orange VS bcbio-nextgen

For all you folks who aren't ace programmer types, the Orange3[1] platform gives you a very miniaturized[2] ability to turn out these sorts of visualizations very rapidly. It's not the most stable thing in the world, but the node-based ML workflow designer is worth the price of admission all by itself.

[1] https://orangedatamining.com/

[2] The Wikipedia extension in Text limits each search result to 25 articles, so sucking all of Wikipedia is . . well, Orange text analytics crashes when I look at it sideways with a null character, so let's not think about what would happen.

First is identifying the "similar" things in a corpus. Best way I know to do that, for non-programmer audiences, is the Orange Data Mining tool, which gives you a node-based text mining interface to perform statistical analysis on text. Hierarchical Clustering shows - very rapidly - how similar your "modules" are, which ones are most similar. There's many other techniques (semantic viewer, similarity hash, etc) as well - the right one will depend on how your content is laying about.

Both tools are ripoffs of a data mining framework named Orange 3

You should also check out Orange Data Mining, it allows to create a lot of charts, filter data from a chart to another, build ML models, predictions and a lot more. And you can do it with zero code.

You can start with a free GUI based tool Orange. It is a component based data science workflow tool, which you can use to handle 60-75% of the traditional data science tasks from classification, regression, to basic neural networks.

Have you tried Orange? https://orangedatamining.com/ This is not a direct answer to your question but Orange has Python based stuff for data mining and visualization. It is very intuitive as for being a graphical interface.

Re WGS there are a lot of well established tool chains that are FLOSS (eg https://github.com/bcbio/bcbio-nextgen). You could run alignment and variant calling on a beefy workstation. A laptop would potentially work. Easy to test this with publicly available raw data. Another option: The sequencing provider often will run alignment and some default variant calling for you. Annotating and analysing these variants can be done on pretty much any computer, all with open source software. A SNP chip is even easier to deal with as the computational requirements are less.

Interpreting the results is a more manual process. Really depends on what you are interested in.

There are plenty of workshops and free documentation online, a few from the top of my head : https://hbctraining.github.io/main/, https://software-carpentry.org/lessons/, https://github.com/bcbio/bcbio-nextgen.