Hail VS poly

Compare Hail vs poly and see what are their differences.

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Hail poly
5 24
932 647
1.2% 2.3%
9.8 8.2
6 days ago 27 days ago
Python Go
MIT License MIT License
The number of mentions indicates the total number of mentions that we've tracked plus the number of user suggested alternatives.
Stars - the number of stars that a project has on GitHub. Growth - month over month growth in stars.
Activity is a relative number indicating how actively a project is being developed. Recent commits have higher weight than older ones.
For example, an activity of 9.0 indicates that a project is amongst the top 10% of the most actively developed projects that we are tracking.

Hail

Posts with mentions or reviews of Hail. We have used some of these posts to build our list of alternatives and similar projects. The last one was on 2023-01-09.
  • We're wasting money by only supporting gzip for raw DNA files
    6 projects | news.ycombinator.com | 9 Jan 2023
  • Software engineers: consider working on genomics
    6 projects | news.ycombinator.com | 19 Nov 2022
    I don't have any funding to hire right now, but I'm always happy to chat about the industry and my experience building Hail (https://hail.is, https://github.com/hail-is/hail), a tool widely used by folks with large collections of human sequences.

    The other posters are not wrong about compensation. Total compensation is off by a factor of two to three.

    However, it is absolutely possible to work with a group of top-notch engineers on serious distributed systems & compilers in service of an excellent scientific-user experience. I know because I do. We are lucky to have a PI who respects and hires and diversity of expertise within his lab.

    I enjoy being deeply embedded with our users. I do not have to guess what they need or want because I help them do it every day.

    I also enjoy enmeshing engineering with statistics, mathematics, and biology. Work is more interesting when so many disciplines conspire towards the end of improved human health.

  • Ask HN: Who is hiring? (July 2021)
    33 projects | news.ycombinator.com | 1 Jul 2021
    Broad Institute of MIT and Harvard | Cambridge, MA | Associate Software Engineer | Onsite

    We are seeking an associate software engineer interested in contributing to an open-source data visualization library for analyzing the biological impact human genetic variation. You will contribute to projects like gnomAD (https://gnomad.broadinstitute.org), the world's largest catalogue of human genetic variation used by hundreds of thousands of researchers and help us scale towards millions of genomes in the coming years. We are also developing next-generation tools for enabling genetic analyses of large biobanks across richly phenotyped individuals (https://genebass.org). In this role you will gain experience developing data-intensive web applications with Typescript, React, Python, Terraform, Google Cloud Platform, and will make use of the scalable data analysis library Hail (https://hail.is). Key to our success is growing a strong team with a diverse membership who foster a culture of continual learning, and who support the growth and success of one another. Towards this end, we are committed to seeking applications from women and from underrepresented groups. We know that many excellent candidates choose not to apply despite their capabilities; please allow us to enthusiastically counter this tendency.

    Please provide a CV and links previous work or projects, ideally with contributions visible on Github.

    email: [email protected]

poly

Posts with mentions or reviews of poly. We have used some of these posts to build our list of alternatives and similar projects. The last one was on 2023-04-13.
  • GitHub Accelerator: our first cohort and what's next
    28 projects | news.ycombinator.com | 13 Apr 2023
    - https://github.com/TimothyStiles/poly: Poly is a fast, well tested Go package for engineering organisms.
  • These 20 startups are in 1st ever batch of GitHub OS Accelerator
    7 projects | /r/github | 12 Apr 2023
    Poly: Fast Go package for engineering organisms
  • Ask HN: Burnt out from big tech. What's next?
    2 projects | news.ycombinator.com | 9 Feb 2023
    You might want to look at computational biology. Jim Allison won the Nobel Prize back in 2018 for his work on immunotherapy for cancer and there's a lot of basic research work to be done to perfect this approach. Epigenetic clocks are really interesting too (see Steve Horvath's work). Also, there's synthetic biology, where you could, for example, explore this package that's written in Go: https://github.com/TimothyStiles/poly
  • Where can I find well-written go code to learn from?
    14 projects | /r/golang | 10 Jan 2023
  • High-performance language recommendation
    3 projects | /r/bioinformatics | 1 Jan 2023
    Check out poly. It’s written in go and I’m using it for one of my projects too. The goal is that we should have high performance libraries that we can use knowing what people are working on the forks will give the community a leg up.
  • How is GO used in bioinfo?
    2 projects | /r/bioinformatics | 27 Dec 2022
    The most popular bioinformatic package I've seen in go is poly.
  • Software engineers: consider working on genomics
    6 projects | news.ycombinator.com | 19 Nov 2022
    I write synthetic biology software for a living and maintain this open source, Go package for engineering DNA that has high test coverage and a nice little dev community around it.

    https://github.com/TimothyStiles/poly

    A large part of my project's community are devs that want to get into the field but can't tolerate the ridiculously low pay, laughably bad management, disrespect, and what amounts to 40+ years of technical debt that's endemic to biotech software.

    I've had companies here in the Bay Area offer me 100K a year with a straight face. I've had companies during interview tell me they're looking for someone to help, "set up GitHub". I've seen job listings for low paid web dev positions require applicants to have PhDs.

    The reality is that except for a growing handful of places management straight up won't know the difference between IT and software engineers. It's what I call the naive buyers problem.

    The demand for software engineers in biotech is generated by naive buyers that don't know what they need, why they need it, or how to get it.

    Benchling and Recursion Pharmaceuticals have reputations in the industry of paying, "standard software salaries". So do the research divisions at places like deepmind/microsoft/google but in my experience there's even new multi-billion dollar institutes where senior management has never even heard the term devops.

    Most places advertise for "data scientist", positions or some analog, instead of software engineers. This is mostly because upper management has never met an actual practicing software engineer in a professional setting. Many come from academia where the culture and work requirements heavily disincentivize standard software engineering practices.

    It's also not uncommon for a biotech company to either have a very under qualified CTO whose main programming experience is what they learned doing ML research like stuff during their PhD or not even have one at all which has huge downstream consequences.

    This week a software engineer trying to make the switch to biotech actually DM'd me to ask why they were seeing a ton of data science / ML job positions but no software engineering / devops positions.

    They were worried that these companies were trying to save on costs by forcing their data scientists to create infrastructure but it's actually worse than that. Most of these companies aren't even aware that there's supposed to be infrastructure.

    Despite all of this the future is looking better and I'm starting to find new companies and positions that are well... reasonable. I learned about this thread from a friend at a party last night that works at one of these companies. There's a small, strong new wave of companies and developers out there pushing biotech software forward. Hopefully some (including myself) make it big while pushing the idea that better tech equals better biotech.

  • Ask HN: What interesting problems are you working on? ( 2022 Edition)
    29 projects | news.ycombinator.com | 16 Sep 2022
    A couple of years ago I realized that there weren't any good open source software packages for designing DNA so I wrote one.

    https://github.com/TimothyStiles/poly

    Goal is to have a suite of packages and databases that can be used to design entirely novel proteins, metabolic pathways, and DNA constructs at scale because right now that software ecosystem just doesn't exist.

    29 projects | news.ycombinator.com | 16 Sep 2022
    It is more like the X Y Z W. However, the X Y Z W bits I am working on as well (https://github.com/TimothyStiles/poly , https://github.com/TimothyStiles/allbase , trilo.bio, freegenes.org). Going for fully automated "make bacterium X produce molecule Y", but still a while away (but surprisingly not THAT far off)
  • Ask HN: What's the best source code you've read?
    46 projects | news.ycombinator.com | 10 Sep 2022
    Not that I understand any of the organic science behind it, but Timothy Stiles' Poly is some of the most beautiful Go code I've seen: https://github.com/TimothyStiles/poly

    Blew my mind reading through it, honestly. Just perfect.

What are some alternatives?

When comparing Hail and poly you can also consider the following projects:

GridScale - Scala library for accessing various file, batch systems, job schedulers and grid middlewares.

Vegas - The missing MatPlotLib for Scala + Spark

metorikku - A simplified, lightweight ETL Framework based on Apache Spark

Scoozie - Scala DSL on top of Oozie XML

Jupyter Scala - A Scala kernel for Jupyter

Scoobi - A Scala productivity framework for Hadoop.

Summingbird - Streaming MapReduce with Scalding and Storm

TileDB-VCF - Efficient variant-call data storage and retrieval library using the TileDB storage library.

Apache Kafka - Mirror of Apache Kafka

Sparkplug - Spark package to "plug" holes in data using SQL based rules ⚡️ 🔌

Apache Spark - Apache Spark - A unified analytics engine for large-scale data processing

Sparkta - Real Time Analytics and Data Pipelines based on Spark Streaming